| Oct. 1946 | Foundation of HEFA-FRENON ARZNEIMITTEL GMBH & CO. KG by the parent company Hefe- und Spiritusfabrik R. Moormann (founded in 1737)
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| Jul. 1975 | Setting up of the daughter company SANAVITA Gesundheitsmittel GmbH & Co. KG. SANAVITA Gesundheitsmittel GmbH & Co. KG is the legal successor of Hefa-Frenon Arzneimittel GmbH & Co. KG
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| Nov. 1998 | Change in ownership. Sole proprietor of the companies SANAVITA Gesundheitsmittel GmbH & Co. KG und Hefa Pharma Vertriebs GmbH & Co. KG: Michael Ostermann
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| Jan. 2002 | Merger of Hefa Pharma Vertriebs GmbH & Co. KG and Michael Ostermann International Agencies with SANAVITA Gesundheitsmittel GmbH & Co. KG into the SANAVITA Aktiengesellschaft & Co.
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| Nov. 2005 | Transfer of SANAVITA Aktiengesellschaft & Co. into SANAVITA Pharmaceuticals GmbH. Main Shareholder: Riemser Arzneimittel AG
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